The Resistance of Rabbits to Tuberculosis after Vaccination with Partially Defatted Tubercle Bacilli
نویسنده
چکیده
1. A vaccine prepared from partially defatted bovine tubercle bacilli influenced favorably the survival time after inoculation with living virulent bovine tubercle bacilli. 2. Accompanying this increased resistance was a sustained lymphocytosis in the vaccinated animals. 3. The vaccine induced a transitory anemia and leucopenia. 4. A similar preparation of partially defatted human tubercle bacilli possessed the power to sensitize guinea pigs to tuberculo-protein.
منابع مشابه
On the Response of Genetically Resistant and Susceptible Rabbits to the Quantitative Inhalation of Human Type Tubercle Bacilli and the Nature of Resistance to Tuberculosis
If genetically resistant and susceptible rabbits inhale a certain number of human type tubercle bacilli, no tuberculosis in the lungs of the resistant animals is seen, as a rule several months after infection, while there is a variable and often extensive disease in the susceptible rabbits. The analogy to the presence or absence of active tuberculosis in man infected with the tubercle bacillus ...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 58 شماره
صفحات -
تاریخ انتشار 2003